On subcritically Stein fillable 5-manifolds

We make some elementary observations concerning subcritically Stein fillable contact structures on 5-manifolds. Specifically, we determine the diffeomorphism type of such contact manifolds in the case the fundamental group is finite cyclic, and we show that on the 5-sphere the standard contact structure is the unique subcritically fillable one. More generally, it is shown that subcritically fillable contact structures on simply connected 5-manifolds are determined by their underlying almost contact structure. Along the way, we discuss the homotopy classification of almost contact structures.Comment: 10 pages; v2: changes to the expositio

Exploiting Point-Wise Attention in 6D Object Pose Estimation Based on Bidirectional Prediction

Traditional geometric registration based estimation methods only exploit the CAD model implicitly, which leads to their dependence on observation quality and deficiency to occlusion. To address the problem,the paper proposes a bidirectional correspondence prediction network with a point-wise attention-aware mechanism. This network not only requires the model points to predict the correspondence but also explicitly models the geometric similarities between observations and the model prior. Our key insight is that the correlations between each model point and scene point provide essential information for learning point-pair matches. To further tackle the correlation noises brought by feature distribution divergence, we design a simple but effective pseudo-siamese network to improve feature homogeneity. Experimental results on the public datasets of LineMOD, YCB-Video, and Occ-LineMOD show that the proposed method achieves better performance than other state-of-the-art methods under the same evaluation criteria. Its robustness in estimating poses is greatly improved, especially in an environment with severe occlusions

Numerical investigation on the cavitating wake flow around a cylinder based on proper orthogonal decomposition

The non-cavitating and cavitating wake flow of a circular cylinder, which contains multiscale vortices, is numerically investigated by Large Eddy Simulation combined with the Schnerr–Sauer cavitation model in this paper. In order to investigate the spatiotemporal evolution of cavitation vortex structures, the Proper Orthogonal Decomposition (POD) method is employed to perform spatiotemporal decomposition on the cylinder wake flow field obtained by numerical simulation. The results reveal that the low-order Proper Orthogonal Decomposition modes correspond to large-scale flow structures with relatively high energy and predominantly single frequencies in both non-cavitating and cavitating conditions. The presence of cavitation bubbles in the flow field leads to a more pronounced deformation of the vortex structures in the low-order modes compared to the non-cavitating case. The dissipation of pressure energy in the cylinder non-cavitating wake occurs faster than the kinetic energy. While in the cavitating wake, the kinetic energy dissipates more rapidly than the pressure energy

Numerical investigation of energy loss distribution in the cavitating wake flow around a cylinder using entropy production method

The wake flow of a circular cylinder is numerically investigated by Large Eddy Simulation (LES) combined with the Schnerr–Sauer cavitation model. By comparing entropy production in the presence or absence of cavitation, the energy loss distribution in the wake flow field of a cylinder is explored, shedding light on the interactions between multiscale vortex systems and cavitation. The comparative results reveal that, under non-cavitating conditions, the energy loss region in the near-wake area is more concentrated and relatively larger. Energy dissipation in the wake flow field occurs in regions characterized by very high velocity gradients, primarily near the upper and lower surfaces of the cylinder near the leading edge. The influence of cavitation bubbles on entropy production is predominantly observed in the trailing-edge region (W1) and the near-wake region (W2). The distribution trends of wall entropy production on the cylinder’s surface are generally consistent in both conditions, with wall entropy production primarily concentrated in regions exhibiting high velocity gradients

Oil and gas prediction basing on seismic inversion of elastic properties in Chaoshan depression, south China sea

The marine Mesozoic is widely distributed in the northeastern waters of the South China Sea and is an important field for oil-gas exploration in the South China Sea. The Chaoshan Depression is the largest residual depression in this sea. At a previous well, LF35-1-1, no oil and gas have been discovered with then pre-drilling prediction techniques. Post-drill analysis shows that the physical properties of the Mesozoic reservoir are not favorable there. So, in accurate prediction of the oil-gas reservoirs is necessary. Since the drilling at the LF35-1-1, extensive surveys and studies have been carried out which shows a number of favorable trapping structures. In the middle low bulge of the Chaoshan Depression, the DS-A structures found with potential reservoirs, complete trap structures, and dual source hydrocarbon supply on both sides, making it the most favorable zone for oil-gas accumulation. We apply the state of art prediction techniques for it using pre-stack seismic raw gather. The sensitivity analysis results of reservoir physical properties indicate that the difference in P- wave velocity between sand and mudstone is 500 m/s, the difference in density is 0.02 g/cm3, and the Poisson’s ratio ranges between 0.11 and 0.33. The Mesozoic sandstone reservoirs in the Chaoshan Depression have characteristics of high velocity and low Poisson’s ratio, and the P-wave velocity, density, and Poisson’s ratio are the main sensitive parameters for predicting reservoir and its oil-gas bearing properties. The density inversion, P-wave impedance inversion, and S-wave impedance inversion jointly characterize the “wedge-shaped” sand body in the DS-A structural area, with a maximum thickness of over 400 m and an area of ∼130 km2. The overlap of the sand body contour map and Poisson’s ratio inversion results indicates that the “wedge-shaped” sand body is an oil-gas bearing sand body. It can be concluded that pre-stack elastic parameter inversion is an effective method for reservoir prediction in deep-sea no-well exploration areas. It has the characteristics of high signal-to-noise ratio, strong stability and reliability, and high accuracy, which is conducive to reduce the non-uniqueness and uncertainty of seismic inversion. The inversion results predict that the DS-A structure is an oil-gas bearing structure

The differential diagnosis value of radiomics-based machine learning in Parkinson’s disease: a systematic review and meta-analysis

BackgroundIn recent years, radiomics has been increasingly utilized for the differential diagnosis of Parkinson’s disease (PD). However, the application of radiomics in PD diagnosis still lacks sufficient evidence-based support. To address this gap, we carried out a systematic review and meta-analysis to evaluate the diagnostic value of radiomics-based machine learning (ML) for PD.MethodsWe systematically searched Embase, Cochrane, PubMed, and Web of Science databases as of November 14, 2022. The radiomics quality assessment scale (RQS) was used to evaluate the quality of the included studies. The outcome measures were the c-index, which reflects the overall accuracy of the model, as well as sensitivity and specificity. During this meta-analysis, we discussed the differential diagnostic value of radiomics-based ML for Parkinson’s disease and various atypical parkinsonism syndromes (APS).ResultsTwenty-eight articles with a total of 6,057 participants were included. The mean RQS score for all included articles was 10.64, with a relative score of 29.56%. The pooled c-index, sensitivity, and specificity of radiomics for predicting PD were 0.862 (95% CI: 0.833–0.891), 0.91 (95% CI: 0.86–0.94), and 0.93 (95% CI: 0.87–0.96) in the training set, and 0.871 (95% CI: 0.853–0.890), 0.86 (95% CI: 0.81–0.89), and 0.87 (95% CI: 0.83–0.91) in the validation set, respectively. Additionally, the pooled c-index, sensitivity, and specificity of radiomics for differentiating PD from APS were 0.866 (95% CI: 0.843–0.889), 0.86 (95% CI: 0.84–0.88), and 0.80 (95% CI: 0.75–0.84) in the training set, and 0.879 (95% CI: 0.854–0.903), 0.87 (95% CI: 0.85–0.89), and 0.82 (95% CI: 0.77–0.86) in the validation set, respectively.ConclusionRadiomics-based ML can serve as a potential tool for PD diagnosis. Moreover, it has an excellent performance in distinguishing Parkinson’s disease from APS. The support vector machine (SVM) model exhibits excellent robustness when the number of samples is relatively abundant. However, due to the diverse implementation process of radiomics, it is expected that more large-scale, multi-class image data can be included to develop radiomics intelligent tools with broader applicability, promoting the application and development of radiomics in the diagnosis and prediction of Parkinson’s disease and related fields.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=383197, identifier ID: CRD42022383197

Dietary specialization drives multiple independent losses and gains in the bitter taste gene repertoire of Laurasiatherian Mammals

Background: Bitter taste perception is essential for species with selective food intake, enabling them to avoid unpalatable or toxic items. Previous studies noted a marked variation in the number of TAS2R genes among various vertebrate species, but the underlying causes are not well understood. Laurasiatherian mammals have highly diversified dietary niche, showing repeated evolution of specialized feeding preferences in multiple lineages and offering a unique chance to investigate how various feeding niches are associated with copy number variation for bitter taste receptor genes. Results: Here we investigated the evolutionary trajectories of TAS2Rs and their implications on bitter taste perception in whole-genome assemblies of 41 Laurasiatherian species. The number of intact TAS2Rs copies varied considerably, ranging from 0 to 52. As an extreme example of a narrow dietary niche, the Chinese pangolin possessed the lowest number of intact TAS2Rs (n = 2) among studied terrestrial vertebrates. Marine mammals (cetacea and pinnipedia), which swallow prey whole, presented a reduced copy number of TAS2Rs (n = 0-5). In contrast, independent insectivorous lineages, such as the shrew and insectivorous bats possessed a higher TAS2R diversity (n = 52 and n = 20-32, respectively), exceeding that in herbivores (n = 9-22) and omnivores (n = 18-22). Conclusions: Besides herbivores, insectivores in Laurasiatheria tend to have more functional TAS2Rs in comparison to carnivores and omnivores. Furthermore, animals swallowing food whole (cetacean, pinnipedia and pangolin) have lost most functional TAS2Rs. These findings provide the most comprehensive view of the bitter taste gene repertoire in Laurasiatherian mammals to date, casting new light on the relationship between losses and gains of TAS2Rs and dietary specialization in mammals